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Tonight, the wife and I decided to give the game a go. As I had spent the previous night pouring over the rules, I played the part of the genestealers, while my wife played the zealous marines.
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The game was very fun, and we both enjoyed the forced timing keeping things moving. All in all, this was a glorious success, and she's looking forward to Captain Raphael's next orders in the second mission.
... as far as that inconsistency I mentioned earlier, it involves Brother Valencio. His unique heraldry has shoe-horned him as the chain-fist model. Valencio is part of Lorenzo's squad, and several times makes reference to the debt he owes Lorenzo. Yet in the mission set-ups, Lorenzo's squad doesn't have a chainfist... Gideon's squad does (none of Gideon's squad's models come with a chainfist). Small oversight on their part, but easily forgivable. I simply swap Valencio's model with Scipio's for the missions.